Bortezomib-mediated expression of p27Kip1 through S-phase kinase protein 2 degradation in epithelial ovarian cancer. [electronic resource]
Producer: 20091027Description: 1115-27 p. digitalISSN:- 1530-0307
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Boronic Acids -- pharmacology
- Bortezomib
- Carcinoma -- drug therapy
- Caspases -- metabolism
- Cell Cycle -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cisplatin -- therapeutic use
- Cyclin-Dependent Kinase Inhibitor p27
- Down-Regulation
- Enzyme Activation -- drug effects
- Female
- Gene Expression Profiling
- Humans
- Intracellular Signaling Peptides and Proteins -- metabolism
- Mice
- Mice, Nude
- Mitochondria -- drug effects
- Oligonucleotide Array Sequence Analysis
- Ovarian Neoplasms -- drug therapy
- Proteasome Inhibitors
- Pyrazines -- pharmacology
- S-Phase Kinase-Associated Proteins -- metabolism
- Tissue Array Analysis
- Transplantation, Heterologous
- Up-Regulation
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Publication Type: Journal Article
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