Peptidoglycan enhances IL-6 production in human synovial fibroblasts via TLR2 receptor, focal adhesion kinase, Akt, and AP-1- dependent pathway. [electronic resource]
Producer: 20090909Description: 2785-92 p. digitalISSN:- 1550-6606
- Adjuvants, Immunologic -- metabolism
- Arthritis, Rheumatoid -- immunology
- Cells, Cultured
- Fibroblasts -- immunology
- Focal Adhesion Kinase 1 -- physiology
- Gene Expression Regulation -- immunology
- Humans
- Inflammation Mediators -- metabolism
- Interleukin-6 -- biosynthesis
- Peptidoglycan -- pharmacology
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- physiology
- Signal Transduction -- immunology
- Synovial Membrane -- enzymology
- Toll-Like Receptor 2 -- physiology
- Transcription Factor AP-1 -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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