Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model. [electronic resource]
Producer: 20090915Description: 2187-97 p. digitalISSN:- 1097-0215
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Capecitabine
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Colorectal Neoplasms -- drug therapy
- Curcumin -- pharmacology
- Cyclin D1 -- genetics
- Cyclooxygenase 2 -- genetics
- Deoxycytidine -- analogs & derivatives
- Drug Synergism
- Fluorouracil -- analogs & derivatives
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Male
- Matrix Metalloproteinase 9 -- genetics
- Mice
- NF-kappa B -- antagonists & inhibitors
- Neoplasm Metastasis -- prevention & control
- Receptors, CXCR4
- Vascular Endothelial Growth Factor A -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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