The anti-histaminic cyproheptadine synergizes the antineoplastic activity of bortezomib in mantle cell lymphoma through its effects as a histone deacetylase inhibitor. [electronic resource]
Producer: 20100222Description: 656-9 p. digitalISSN:- 1365-2141
- Actins -- metabolism
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Apoptosis -- drug effects
- Boronic Acids -- administration & dosage
- Bortezomib
- Cyclin D1 -- metabolism
- Cyproheptadine -- administration & dosage
- Disease Models, Animal
- Histamine H1 Antagonists -- pharmacology
- Histone Deacetylase Inhibitors
- Lymphoma, Mantle-Cell -- drug therapy
- Mice
- Protease Inhibitors -- pharmacology
- Pyrazines -- administration & dosage
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Publication Type: Journal Article
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