Complete protection against experimental visceral leishmaniasis with complete soluble antigen from attenuated Leishmania donovani promastigotes involves Th1-immunity and down-regulation of IL-10. [electronic resource]
Producer: 20090916Description: 2146-60 p. digitalISSN:- 1521-4141
- Animals
- Antigens, Protozoan -- administration & dosage
- Clonal Anergy -- immunology
- Cricetinae
- Cytokines -- genetics
- Down-Regulation
- Gene Expression
- Immunization -- methods
- Interferon-gamma -- metabolism
- Interleukin-4 -- metabolism
- Leishmania donovani -- immunology
- Leishmaniasis, Visceral -- immunology
- Liver Diseases, Parasitic -- immunology
- Macrophage Activation -- immunology
- Macrophages -- immunology
- Mesocricetus
- Mice
- Mice, Inbred BALB C
- Reverse Transcriptase Polymerase Chain Reaction
- Spleen -- immunology
- T-Lymphocytes -- immunology
- Th1 Cells -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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