Methotrexate-induced apoptosis is enhanced by altered expression of methylenetetrahydrofolate reductase. [electronic resource]
Producer: 20091231Description: 787-93 p. digitalISSN:- 1473-5741
- Animals
- Antimetabolites, Antineoplastic -- pharmacology
- Apoptosis -- drug effects
- Caspase 3 -- metabolism
- Caspase 7 -- metabolism
- Gene Expression
- Homocysteine -- blood
- Methotrexate -- pharmacology
- Methylenetetrahydrofolate Reductase (NADPH2) -- genetics
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Spleen -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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