HDAC inhibitor, scriptaid, induces glioma cell apoptosis through JNK activation and inhibits telomerase activity. [electronic resource]
Producer: 20110302Description: 2151-61 p. digitalISSN:- 1582-4934
- Acetylation -- drug effects
- Anthracenes -- pharmacology
- Apoptosis -- drug effects
- Blotting, Western
- Cell Cycle -- drug effects
- Cell Cycle Proteins -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- DNA Damage
- Dose-Response Relationship, Drug
- Enzyme Activation -- drug effects
- Enzyme-Linked Immunosorbent Assay
- Glioma -- genetics
- Histone Deacetylase Inhibitors -- pharmacology
- Histone Deacetylases -- metabolism
- Histones -- metabolism
- Humans
- Hydroxylamines -- pharmacology
- JNK Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- Polymerase Chain Reaction -- methods
- Quinolines -- pharmacology
- Signal Transduction -- drug effects
- Telomerase -- antagonists & inhibitors
- ras Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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