(-)-Epigallocatechin gallate attenuates the induction of HSP27 stimulated by sphingosine 1-phosphate via suppression of phosphatidylinositol 3-kinase/Akt pathway in osteoblasts. [electronic resource]
Producer: 20090924Description: 197-203 p. digitalISSN:- 1107-3756
- Animals
- Animals, Newborn
- Blotting, Western
- Catechin -- analogs & derivatives
- Cell Line
- Cells, Cultured
- Dose-Response Relationship, Drug
- HSP27 Heat-Shock Proteins -- metabolism
- Intracellular Signaling Peptides and Proteins -- metabolism
- Lysophospholipids -- pharmacology
- Mice
- Microscopy, Fluorescence
- Models, Biological
- Osteoblasts -- cytology
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphorylation -- drug effects
- Protein Serine-Threonine Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction -- drug effects
- Sphingosine -- analogs & derivatives
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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