Mice with altered myelin proteolipid protein gene expression display cognitive deficits accompanied by abnormal neuron-glia interactions and decreased conduction velocities. [electronic resource]
Producer: 20090720Description: 8363-71 p. digitalISSN:- 1529-2401
- Adaptation, Psychological -- physiology
- Analysis of Variance
- Animals
- Axons -- pathology
- Central Nervous System -- metabolism
- Cognition Disorders -- genetics
- Exploratory Behavior -- physiology
- Gene Expression Regulation
- Hand Strength -- physiology
- Inhibition, Psychological
- Kv1.2 Potassium Channel -- metabolism
- Maze Learning -- physiology
- Mice
- Mice, Inbred Strains
- Mice, Transgenic
- Microscopy, Electron, Transmission
- Myelin Proteolipid Protein -- genetics
- Nerve Fibers, Myelinated -- pathology
- Neural Conduction -- genetics
- Neuroglia -- physiology
- Neurons -- pathology
- Neuropsychological Tests
- Pain Threshold -- physiology
- Psychomotor Performance -- physiology
- Ranvier's Nodes -- pathology
- Reflex, Startle -- genetics
- Swimming -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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