A highly selective, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor has potent activity in vitro and in vivo. [electronic resource]
Producer: 20100111Description: 287-96 p. digitalISSN:- 1573-7209
- Administration, Oral
- Angiogenesis Inhibitors -- administration & dosage
- Animals
- Cell Movement -- drug effects
- Cells, Cultured
- Endothelial Cells -- drug effects
- Female
- HCT116 Cells
- Humans
- Mice
- Mice, Inbred C57BL
- Mice, Nude
- Mice, Transgenic
- Models, Biological
- Neoplasms -- drug therapy
- Oximes -- administration & dosage
- Phenylurea Compounds -- administration & dosage
- Protein Kinase Inhibitors -- administration & dosage
- Substrate Specificity
- Vascular Endothelial Growth Factor A -- pharmacology
- Vascular Endothelial Growth Factor Receptor-2 -- antagonists & inhibitors
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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