DSM-RX78, a new phosphodiesterase inhibitor, suppresses superoxide anion production in activated human neutrophils and attenuates hemorrhagic shock-induced lung injury in rats. [electronic resource]
Producer: 20091019Description: 983-92 p. digitalISSN:- 1873-2968
- Adult
- Animals
- Benzamides -- chemistry
- Benzoates -- chemistry
- Bronchoalveolar Lavage Fluid -- chemistry
- Cyclic AMP -- biosynthesis
- Cyclic AMP-Dependent Protein Kinases -- analysis
- Dose-Response Relationship, Drug
- Humans
- Inhibitory Concentration 50
- Leukocyte Elastase -- antagonists & inhibitors
- Lung Injury -- etiology
- Lymphocyte Activation -- drug effects
- Male
- Molecular Structure
- N-Formylmethionine Leucyl-Phenylalanine -- pharmacology
- Neutrophils -- drug effects
- Phosphodiesterase Inhibitors -- chemistry
- Proteins -- analysis
- Random Allocation
- Rats
- Rats, Sprague-Dawley
- Respiratory Burst
- Shock, Hemorrhagic -- metabolism
- Superoxides -- antagonists & inhibitors
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.