Global and gene-specific promoter methylation changes are related to anti-B[a]PDE-DNA adduct levels and influence micronuclei levels in polycyclic aromatic hydrocarbon-exposed individuals. [electronic resource]
Producer: 20090828Description: 1692-7 p. digitalISSN:- 1097-0215
- Adult
- Base Sequence
- Biomarkers -- blood
- Case-Control Studies
- Coke
- DNA Adducts -- blood
- DNA Methylation
- Genes, p53
- Humans
- Inhalation Exposure
- Kruppel-Like Transcription Factors
- Linear Models
- Male
- Micronuclei, Chromosome-Defective
- Middle Aged
- Molecular Sequence Data
- Occupational Exposure -- adverse effects
- Poland
- Polycyclic Aromatic Hydrocarbons -- toxicity
- Polymerase Chain Reaction
- Promoter Regions, Genetic
- Sequence Analysis, DNA
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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