Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs. [electronic resource]
Producer: 20091209Description: 1093-108 p. digitalISSN:- 1557-8534
- Animals
- Cell Differentiation -- physiology
- Cell Transformation, Neoplastic -- genetics
- DNA Methylation -- physiology
- Epigenesis, Genetic -- physiology
- Homeodomain Proteins -- genetics
- Humans
- MicroRNAs -- genetics
- Nanog Homeobox Protein
- Neoplastic Stem Cells -- cytology
- Octamer Transcription Factor-3 -- genetics
- Pluripotent Stem Cells -- cytology
- SOXB1 Transcription Factors -- genetics
- Transcription, Genetic -- physiology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review
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