Combination therapy using chimeric monoclonal antibodies protects mice from lethal H5N1 infection and prevents formation of escape mutants. [electronic resource]
Producer: 20090720Description: e5672 p. digitalISSN:- 1932-6203
- Animals
- Antibodies, Monoclonal -- administration & dosage
- Antibodies, Viral -- administration & dosage
- Cell Line
- Dogs
- Dose-Response Relationship, Drug
- Drug Therapy, Combination
- Humans
- Immunization, Passive
- Influenza A Virus, H5N1 Subtype -- genetics
- Lung -- pathology
- Mice
- Mutation -- genetics
- Neutralization Tests
- Orthomyxoviridae Infections -- drug therapy
- Reassortant Viruses -- genetics
- Recombinant Fusion Proteins -- administration & dosage
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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