Estrogen inhibits ATR signaling to cell cycle checkpoints and DNA repair. [electronic resource]
Producer: 20091013Description: 3374-89 p. digitalISSN:- 1939-4586
- Animals
- Ataxia Telangiectasia Mutated Proteins
- Cell Cycle -- drug effects
- Cell Cycle Proteins -- antagonists & inhibitors
- Cell Line, Transformed
- Cell Line, Tumor
- Checkpoint Kinase 1
- DNA Repair -- drug effects
- Enzyme Activation -- drug effects
- Epithelial Cells -- cytology
- Estradiol -- pharmacology
- Estrogen Receptor alpha -- metabolism
- Female
- Humans
- Mammary Glands, Animal -- cytology
- Mice
- Mice, Inbred C57BL
- Models, Biological
- Protein Kinase Inhibitors -- pharmacology
- Protein Kinases -- metabolism
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction -- drug effects
- Substrate Specificity -- drug effects
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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