The inhibition of lipopolysaccharide-induced tumor necrosis factor-alpha and nitric oxide production by Clostridium perfringens alpha-toxin and its relation to alpha-toxin-induced intracellular ceramide generation. [electronic resource]
Producer: 20100203Description: 554-62 p. digitalISSN:- 1618-0607
- Animals
- Bacterial Toxins -- immunology
- Calcium-Binding Proteins -- immunology
- Cell Line
- Ceramides -- metabolism
- Gene Expression Regulation -- drug effects
- Genes, Reporter
- I-kappa B Kinase -- metabolism
- Lipopolysaccharides -- immunology
- Luciferases -- biosynthesis
- Macrophages -- chemistry
- Mice
- Nitric Oxide -- antagonists & inhibitors
- Phosphorylation
- Transcription Factor RelA -- metabolism
- Tumor Necrosis Factor-alpha -- antagonists & inhibitors
- Type C Phospholipases -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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