Interstitial flow promotes vascular fibroblast, myofibroblast, and smooth muscle cell motility in 3-D collagen I via upregulation of MMP-1. [electronic resource]
Producer: 20091008Description: H1225-34 p. digitalISSN:- 1522-1539
- Animals
- Apoptosis
- Blood Pressure
- Cell Movement -- drug effects
- Cells, Cultured
- Collagen Type I -- metabolism
- Dipeptides -- pharmacology
- Fibroblasts -- drug effects
- Gels
- Matrix Metalloproteinase 1 -- genetics
- Matrix Metalloproteinase 2 -- metabolism
- Matrix Metalloproteinase Inhibitors
- Mechanotransduction, Cellular -- drug effects
- Models, Biological
- Muscle, Smooth, Vascular -- drug effects
- Myocytes, Smooth Muscle -- drug effects
- Necrosis
- Permeability
- Protease Inhibitors -- pharmacology
- Pulsatile Flow
- RNA Interference
- Rats
- Rheology
- Stress, Mechanical
- Tissue Inhibitor of Metalloproteinase-1 -- metabolism
- Up-Regulation
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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