Dimethylfumarate inhibits NF-{kappa}B function at multiple levels to limit airway smooth muscle cell cytokine secretion. [electronic resource]
Producer: 20090824Description: L326-39 p. digitalISSN:- 1522-1504
- Anti-Inflammatory Agents, Non-Steroidal -- pharmacology
- Becaplermin
- Bronchi -- cytology
- Cells, Cultured
- Chemokine CCL11 -- metabolism
- Chemokine CCL5 -- metabolism
- Chronic Disease
- Cyclic AMP Response Element-Binding Protein -- metabolism
- Cytokines -- metabolism
- Dexamethasone -- pharmacology
- Dimethyl Fumarate
- Enzyme Inhibitors -- pharmacology
- Fumarates -- pharmacology
- Glucocorticoids -- pharmacology
- Humans
- I-kappa B Proteins -- metabolism
- Immunosuppressive Agents -- pharmacology
- Interleukin-6 -- metabolism
- Isoquinolines -- pharmacology
- Myocytes, Smooth Muscle -- cytology
- NF-KappaB Inhibitor alpha
- Platelet-Derived Growth Factor -- metabolism
- Pneumonia -- drug therapy
- Proto-Oncogene Proteins c-sis
- RNA, Small Interfering
- Ribosomal Protein S6 Kinases, 90-kDa -- metabolism
- Sesquiterpenes -- pharmacology
- Sesquiterpenes, Guaiane
- Sulfonamides -- pharmacology
- Transcription Factor RelA -- genetics
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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