Serum factors potentiate hypoxia-induced hepatotoxicity in vitro through increasing transforming growth factor-beta1 activation and release. [electronic resource]
Producer: 20090921Description: 11-22 p. digitalISSN:- 1096-0023
- Animals
- Antibodies, Monoclonal -- immunology
- Apoptosis -- drug effects
- Cell Hypoxia -- drug effects
- Cell Line
- Cell Survival -- drug effects
- Gene Expression -- physiology
- Hepatocytes -- cytology
- Hyaluronan Receptors -- metabolism
- L-Lactate Dehydrogenase -- metabolism
- Matrix Metalloproteinase 9 -- metabolism
- Nitroimidazoles -- metabolism
- Phosphorylation -- drug effects
- Proliferating Cell Nuclear Antigen -- metabolism
- Protein Serine-Threonine Kinases -- metabolism
- Rats
- Rats, Sprague-Dawley
- Receptor, Transforming Growth Factor-beta Type I
- Receptor, Transforming Growth Factor-beta Type II
- Receptors, Transforming Growth Factor beta -- metabolism
- Serum -- physiology
- Smad2 Protein -- metabolism
- Transforming Growth Factor beta1 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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