Effects of polyoxyethylene (40) stearate on the activity of P-glycoprotein and cytochrome P450. [electronic resource]
Producer: 20091112Description: 573-80 p. digitalISSN:- 1879-0720
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- metabolism
- Animals
- Biological Availability
- Biological Transport
- Caco-2 Cells
- Cytochrome P-450 Enzyme System -- metabolism
- Dose-Response Relationship, Drug
- Excipients -- pharmacokinetics
- Humans
- In Vitro Techniques
- Intestinal Mucosa -- metabolism
- Intestines -- drug effects
- Isoenzymes
- Male
- Membrane Fluidity -- drug effects
- Micelles
- Microsomes, Liver -- drug effects
- Polyethylene Glycols -- pharmacokinetics
- Rats
- Rats, Sprague-Dawley
- Rhodamine 123 -- pharmacokinetics
- Rhodamines -- pharmacokinetics
- Substrate Specificity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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