A phase I trial of enzastaurin in patients with recurrent gliomas. [electronic resource]
Producer: 20090803Description: 3617-23 p. digitalISSN:- 1078-0432
- Adult
- Area Under Curve
- Cross-Over Studies
- Dose-Response Relationship, Drug
- Glioma -- drug therapy
- Glycogen Synthase Kinase 3 -- blood
- Glycogen Synthase Kinase 3 beta
- Humans
- Indoles -- adverse effects
- Long QT Syndrome -- chemically induced
- Metabolic Clearance Rate
- Neoplasm Recurrence, Local
- Phosphoproteins -- blood
- Protein Kinase C -- antagonists & inhibitors
- Protein Kinase C beta
- Survival Analysis
- Thrombocytopenia -- chemically induced
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Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
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