Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1. [electronic resource]
Producer: 20090813Description: 422-31 p. digitalISSN:- 0006-3002
- Active Transport, Cell Nucleus -- drug effects
- Amides -- pharmacology
- Aniline Compounds -- pharmacology
- Animals
- Cardiomegaly -- drug therapy
- Cell Nucleus -- drug effects
- Cells, Cultured
- Histone Deacetylase Inhibitors
- Histone Deacetylases -- chemistry
- Humans
- Karyopherins -- antagonists & inhibitors
- Microscopy, Fluorescence
- Myocytes, Cardiac -- drug effects
- Phosphorylation
- Rats
- Rats, Sprague-Dawley
- Receptors, Cytoplasmic and Nuclear -- antagonists & inhibitors
- Structure-Activity Relationship
- Exportin 1 Protein
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Publication Type: Journal Article
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