Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons. [electronic resource]
Producer: 20090520Description: 218-29 p. digitalISSN:- 1097-4199
- Animals
- Animals, Newborn
- Calbindins
- Calcium -- metabolism
- Calcium Channel Blockers -- pharmacology
- Cell Death -- drug effects
- Cytosol -- drug effects
- Dopamine -- metabolism
- Dopamine Agents -- pharmacology
- Dose-Response Relationship, Drug
- Electrochemistry -- methods
- Enzyme Inhibitors -- pharmacology
- Gene Expression Regulation -- drug effects
- Green Fluorescent Proteins -- genetics
- Humans
- Hydrazines -- pharmacology
- Levodopa -- pharmacology
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Neurons -- cytology
- Rats
- Rats, Sprague-Dawley
- S100 Calcium Binding Protein G -- metabolism
- Substantia Nigra -- cytology
- Time Factors
- Tyrosine 3-Monooxygenase -- genetics
- Vesicular Monoamine Transport Proteins -- genetics
- alpha-Synuclein -- deficiency
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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