A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile parasites. [electronic resource]
Producer: 20090610Description: 1601-12 p. digitalISSN:- 1878-5875
- Animals
- Catalytic Domain
- Cathepsin B -- antagonists & inhibitors
- Cathepsins -- antagonists & inhibitors
- Cystatins -- metabolism
- Cysteine Proteinase Inhibitors -- pharmacology
- Enzyme Activation -- drug effects
- Fasciola hepatica -- drug effects
- Gastrointestinal Tract -- enzymology
- Humans
- Kinetics
- Life Cycle Stages -- drug effects
- Molecular Probes -- chemistry
- Parasites -- drug effects
- Protein Transport -- drug effects
- Sheep
- Structural Homology, Protein
- Substrate Specificity -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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