The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression. [electronic resource]
Producer: 20090803Description: 987-93 p. digitalISSN:- 1088-9051
- Aged
- Alleles
- Animals
- Cell Line, Tumor
- Chromosome Mapping
- Chromosomes, Human, Pair 18 -- genetics
- Colorectal Neoplasms -- genetics
- Electrophoretic Mobility Shift Assay
- Female
- Gene Expression
- Gene Frequency
- Genetic Predisposition to Disease -- genetics
- Genetic Variation
- Genotype
- Humans
- Male
- Middle Aged
- Nuclear Proteins -- metabolism
- Polymorphism, Single Nucleotide
- Protein Binding
- Risk Factors
- Sequence Analysis, DNA
- Smad7 Protein -- genetics
- Xenopus laevis -- embryology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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