Forskolin increases angiogenesis through the coordinated cross-talk of PKA-dependent VEGF expression and Epac-mediated PI3K/Akt/eNOS signaling. [electronic resource]
Producer: 20090603Description: 906-15 p. digitalISSN:- 1873-3913
- Animals
- Cell Proliferation -- drug effects
- Chick Embryo
- Colforsin -- pharmacology
- Cyclic AMP -- analogs & derivatives
- Cyclic AMP Response Element-Binding Protein -- metabolism
- Cyclic AMP-Dependent Protein Kinases -- metabolism
- Dinoprostone -- pharmacology
- Endothelial Cells -- cytology
- Enzyme Activation -- drug effects
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Guanine Nucleotide Exchange Factors -- metabolism
- Humans
- Neovascularization, Physiologic -- drug effects
- Nitric Oxide Synthase Type III -- metabolism
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction -- drug effects
- Up-Regulation -- drug effects
- Vascular Endothelial Growth Factor A -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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