The active form of human aryl hydrocarbon receptor (AHR) repressor lacks exon 8, and its Pro 185 and Ala 185 variants repress both AHR and hypoxia-inducible factor. [electronic resource]
Producer: 20090730Description: 3465-77 p. digitalISSN:- 1098-5549
- Alanine -- metabolism
- Amino Acid Sequence
- Animals
- Basic Helix-Loop-Helix Transcription Factors
- Cell Line
- Exons
- Gene Expression Regulation
- Humans
- Hypoxia-Inducible Factor 1 -- genetics
- Mice
- Molecular Sequence Data
- Pregnane X Receptor
- Proline -- metabolism
- Promoter Regions, Genetic
- Protein Isoforms -- genetics
- Receptors, Aryl Hydrocarbon -- genetics
- Receptors, Steroid -- genetics
- Recombinant Fusion Proteins -- genetics
- Repressor Proteins -- genetics
- Sequence Alignment
- Sequence Homology, Amino Acid
- Tissue Distribution
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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