Upregulation of RGS4 expression by IL-1beta in colonic smooth muscle is enhanced by ERK1/2 and p38 MAPK and inhibited by the PI3K/Akt/GSK3beta pathway. [electronic resource]
Producer: 20090709Description: C1310-20 p. digitalISSN:- 0363-6143
- Animals
- Cells, Cultured
- Colon -- cytology
- Glycogen Synthase Kinase 3 -- antagonists & inhibitors
- Glycogen Synthase Kinase 3 beta
- I-kappa B Kinase -- metabolism
- I-kappa B Proteins -- metabolism
- Interleukin-1beta -- metabolism
- Mitogen-Activated Protein Kinase 1 -- antagonists & inhibitors
- Mitogen-Activated Protein Kinase 3 -- antagonists & inhibitors
- Muscle Contraction
- Myocytes, Smooth Muscle -- drug effects
- NF-KappaB Inhibitor alpha
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- Phosphorylation
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-akt -- metabolism
- RGS Proteins -- genetics
- RNA, Messenger -- metabolism
- Rabbits
- Signal Transduction
- Time Factors
- Transcription Factor RelA -- metabolism
- Up-Regulation
- p38 Mitogen-Activated Protein Kinases -- antagonists & inhibitors
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural
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