Simultaneous targeting of MCL1 and ABCB1 as a novel strategy to overcome drug resistance in human leukaemia. [electronic resource]
Producer: 20090803Description: 648-56 p. digitalISSN:- 1365-2141
- ATP Binding Cassette Transporter, Subfamily B
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- genetics
- Antineoplastic Agents -- therapeutic use
- Apoptosis -- drug effects
- Blotting, Western -- methods
- Cell Line, Tumor
- Chi-Square Distribution
- Down-Regulation
- Doxorubicin -- therapeutic use
- Drug Resistance, Neoplasm -- drug effects
- Flow Cytometry
- Gene Expression
- Humans
- Leukemia -- drug therapy
- Myeloid Cell Leukemia Sequence 1 Protein
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- RNA Interference
- RNA, Small Interfering -- pharmacology
- Reverse Transcriptase Polymerase Chain Reaction -- methods
- Transfection -- methods
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Publication Type: Journal Article
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