3-Benzyl-1,3-oxazolidin-2-ones as mGluR2 positive allosteric modulators: Hit-to lead and lead optimization. [electronic resource]
Producer: 20090821Description: 2524-9 p. digitalISSN:- 1464-3405
- Administration, Oral
- Allosteric Regulation
- Allosteric Site
- Carbamates -- chemistry
- Chemistry, Pharmaceutical -- methods
- Drug Design
- Humans
- Inhibitory Concentration 50
- Ligands
- Microsomes -- metabolism
- Models, Chemical
- Molecular Structure
- Oxazolidinones -- chemical synthesis
- Receptors, Metabotropic Glutamate -- antagonists & inhibitors
- Schizophrenia -- drug therapy
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Publication Type: Journal Article
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