Spleen tyrosine kinase functions as a tumor suppressor in melanoma cells by inducing senescence-like growth arrest. [electronic resource]
Producer: 20090602Description: 2748-56 p. digitalISSN:- 1538-7445
- Cell Growth Processes -- physiology
- Cellular Senescence -- physiology
- Chemotaxis
- Cyclin-Dependent Kinase Inhibitor p21 -- biosynthesis
- DNA Methylation
- Humans
- Intracellular Signaling Peptides and Proteins -- genetics
- Melanoma -- enzymology
- Neoplastic Stem Cells -- pathology
- Promoter Regions, Genetic
- Protein-Tyrosine Kinases -- biosynthesis
- RNA, Small Interfering -- genetics
- Signal Transduction
- Spheroids, Cellular
- Syk Kinase
- Transfection
- Tumor Suppressor Protein p53 -- metabolism
- Up-Regulation
- src Homology Domains
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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