Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks. [electronic resource]
Producer: 20090327Description: 547-58 p. digitalISSN:- 1097-4164
- Acid Anhydride Hydrolases
- Ataxia Telangiectasia Mutated Proteins
- Carrier Proteins -- metabolism
- Cell Cycle Proteins -- antagonists & inhibitors
- Checkpoint Kinase 1
- Checkpoint Kinase 2
- DNA Breaks, Double-Stranded
- DNA Repair -- drug effects
- DNA Repair Enzymes -- metabolism
- DNA, Single-Stranded -- metabolism
- DNA-Binding Proteins -- antagonists & inhibitors
- Endodeoxyribonucleases
- Enzyme Activation
- Exodeoxyribonucleases -- metabolism
- HeLa Cells
- Humans
- MRE11 Homologue Protein
- Nuclear Proteins -- metabolism
- Phosphorylation
- Protein Kinase Inhibitors -- pharmacology
- Protein Kinases -- metabolism
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- RNA Interference
- RNA, Small Interfering -- metabolism
- Time Factors
- Transfection
- Tumor Suppressor Proteins -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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