RUNX1 mutations are frequent in chronic myelomonocytic leukemia and mutations at the C-terminal region might predict acute myeloid leukemia transformation. [electronic resource]
Producer: 20090921Description: 1426-31 p. digitalISSN:- 1476-5551
- Adult
- Aged
- Aged, 80 and over
- Blast Crisis -- genetics
- Core Binding Factor Alpha 2 Subunit -- chemistry
- DNA Mutational Analysis
- DNA, Neoplasm -- genetics
- Disease Progression
- Female
- Genes, ras
- Humans
- Kaplan-Meier Estimate
- Leukemia, Myeloid, Acute -- genetics
- Leukemia, Myelomonocytic, Chronic -- genetics
- Male
- Middle Aged
- Mutation
- Neoplasm Proteins -- chemistry
- Prognosis
- Protein Structure, Tertiary
- fms-Like Tyrosine Kinase 3 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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