PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia. [electronic resource]
Producer: 20090415Description: 352-61 p. digitalISSN:- 1538-3687
- Alzheimer Disease -- etiology
- Amyloid Precursor Protein Secretases -- metabolism
- Amyloid beta-Peptides -- metabolism
- Amyloid beta-Protein Precursor -- genetics
- Animals
- Case-Control Studies
- Cells, Cultured
- Culture Media, Conditioned -- chemistry
- Dementia -- complications
- Disease Progression
- Dose-Response Relationship, Drug
- Down-Regulation -- drug effects
- Embryo, Mammalian
- Forkhead Box Protein O3
- Forkhead Transcription Factors -- metabolism
- Gene Expression Profiling -- methods
- Glucose -- pharmacology
- Green Fluorescent Proteins -- genetics
- Heat-Shock Proteins -- genetics
- Hippocampus -- metabolism
- Humans
- Mice
- Mice, Transgenic
- Neurons -- drug effects
- Oligonucleotide Array Sequence Analysis -- methods
- Peptide Fragments -- metabolism
- Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
- RNA, Messenger -- metabolism
- Transcription Factors -- genetics
- Transfection
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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