Myxoma virus selectively disrupts type I interferon signaling in primary human fibroblasts by blocking the activation of the Janus kinase Tyk2. [electronic resource]
Producer: 20090619Description: 136-46 p. digitalISSN:- 1096-0341
- Cells, Cultured
- Enzyme Activation
- Fibroblasts -- metabolism
- Gene Expression Regulation
- Humans
- Interferon Type I -- metabolism
- Myxoma virus -- genetics
- Phosphorylation
- Poxviridae Infections -- physiopathology
- Protein Binding
- Protein Transport
- STAT1 Transcription Factor -- metabolism
- Signal Transduction -- physiology
- TYK2 Kinase -- metabolism
- Tumor Virus Infections -- physiopathology
- Tyrosine -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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