Key residues controlling binding of diverse ligands to human cytochrome P450 2A enzymes. [electronic resource]
Producer: 20090925Description: 1319-27 p. digitalISSN:- 1521-009X
- Amino Acid Sequence
- Amino Acid Substitution
- Aryl Hydrocarbon Hydroxylases -- chemistry
- Catalytic Domain -- drug effects
- Cytochrome P-450 CYP2A6
- Cytochrome P-450 Enzyme System -- chemistry
- Humans
- Ligands
- Microsomes, Liver
- Models, Molecular
- Mutagenesis, Site-Directed
- Protein Binding -- genetics
- Protein Conformation
- Steroid Hydroxylases -- chemistry
- Structure-Activity Relationship
- Substrate Specificity
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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