A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53. [electronic resource]
Producer: 20090326Description: 3964-9 p. digitalISSN:- 1091-6490
- Alleles
- Animals
- Antineoplastic Agents -- pharmacology
- Cell Line, Tumor
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- G1 Phase -- drug effects
- Gene Expression Profiling
- Gene Targeting
- Genotype
- Humans
- Imidazoles -- metabolism
- Mice
- Neoplasms -- pathology
- Piperazines -- metabolism
- Pteridines -- pharmacology
- Transcription, Genetic -- drug effects
- Tumor Suppressor Protein p53 -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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