Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection. [electronic resource]
Producer: 20090624Description: 2089-99 p. digitalISSN:- 1098-6596
- Animals
- Antiviral Agents -- chemistry
- Chlorocebus aethiops
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Ebolavirus -- drug effects
- Female
- Hemorrhagic Fever, Ebola -- drug therapy
- Humans
- Male
- Mice
- Mice, Inbred C57BL
- Morpholines -- chemistry
- Oligonucleotides, Antisense -- chemistry
- Rabbits
- Structure-Activity Relationship
- Treatment Outcome
- Vero Cells
- Virus Replication -- drug effects
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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