Repression of BIRC5/survivin by FOXO3/FKHRL1 sensitizes human neuroblastoma cells to DNA damage-induced apoptosis. [electronic resource]
Producer: 20090701Description: 2041-8 p. digitalISSN:- 1939-4586
- Alleles
- Apoptosis -- drug effects
- Cell Line, Tumor
- DNA Damage
- Doxorubicin -- pharmacology
- Drug Screening Assays, Antitumor
- Etoposide -- pharmacology
- Forkhead Box Protein O3
- Forkhead Transcription Factors -- metabolism
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Inhibitor of Apoptosis Proteins
- Microtubule-Associated Proteins -- antagonists & inhibitors
- Mitochondria -- drug effects
- Neuroblastoma -- enzymology
- Phosphoinositide-3 Kinase Inhibitors
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- RNA, Messenger -- genetics
- RNA, Small Interfering -- metabolism
- Survivin
- Transgenes
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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