DY-9760e inhibits endothelin-1-induced cardiomyocyte hypertrophy through inhibition of CaMKII and ERK activities. [electronic resource]
Producer: 20090326Description: 17-27 p. digitalISSN:- 1755-5914
- Animals
- Animals, Newborn
- Atrial Natriuretic Factor -- metabolism
- Benzylamines -- pharmacology
- Butadienes -- pharmacology
- Calcimycin -- pharmacology
- Calcium Signaling -- drug effects
- Calcium-Calmodulin-Dependent Protein Kinase Type 2 -- antagonists & inhibitors
- Cardiomegaly -- enzymology
- Cell Proliferation -- drug effects
- Cell Size -- drug effects
- Cells, Cultured
- DNA Replication -- drug effects
- Endothelin-1 -- metabolism
- Extracellular Signal-Regulated MAP Kinases -- antagonists & inhibitors
- Indazoles -- pharmacology
- Ionophores -- pharmacology
- Myocytes, Cardiac -- drug effects
- Natriuretic Peptide, Brain -- metabolism
- Nitriles -- pharmacology
- Phosphorylation
- Protein Kinase Inhibitors -- pharmacology
- RNA, Messenger -- metabolism
- Rats
- Rats, Wistar
- Sulfonamides -- pharmacology
- Time Factors
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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