Pioglitazone stimulates AMP-activated protein kinase signalling and increases the expression of genes involved in adiponectin signalling, mitochondrial function and fat oxidation in human skeletal muscle in vivo: a randomised trial. [electronic resource]
Producer: 20090619Description: 723-32 p. digitalISSN:- 1432-0428
- AMP-Activated Protein Kinases -- drug effects
- Adiponectin -- blood
- Blood Glucose -- drug effects
- DNA Primers
- Diabetes Mellitus, Type 2 -- drug therapy
- Diet, Diabetic
- Double-Blind Method
- Fatty Acids, Nonesterified -- blood
- Female
- Gene Expression Regulation -- drug effects
- Glucose Clamp Technique
- Humans
- Hyperinsulinism
- Hypoglycemic Agents -- therapeutic use
- Male
- Malonyl Coenzyme A -- metabolism
- Middle Aged
- Mitochondria, Muscle -- metabolism
- Pioglitazone
- Polymerase Chain Reaction
- RNA, Messenger -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Thiazolidinediones -- therapeutic use
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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