FKBP25, a novel regulator of the p53 pathway, induces the degradation of MDM2 and activation of p53. [electronic resource]
Producer: 20090320Description: 621-6 p. digitalISSN:- 1873-3468
- Animals
- Cell Line, Tumor
- Cyclin-Dependent Kinase Inhibitor p21 -- genetics
- Escherichia coli -- genetics
- Gene Expression Regulation, Neoplastic
- Genes, Reporter
- Glutathione Transferase -- metabolism
- HCT116 Cells
- Humans
- Luciferases -- metabolism
- Mice
- Proteasome Endopeptidase Complex -- genetics
- Proto-Oncogene Proteins c-mdm2 -- genetics
- RNA, Small Interfering -- metabolism
- Recombinant Fusion Proteins -- metabolism
- Tacrolimus Binding Proteins -- genetics
- Transfection
- Tumor Suppressor Protein p53 -- genetics
- Ubiquitin-Protein Ligases -- genetics
- Ubiquitination
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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