Inhibition of focal adhesion kinase as a potential therapeutic strategy for imatinib-resistant gastrointestinal stromal tumor. [electronic resource]
Producer: 20090219Description: 127-34 p. digitalISSN:- 1535-7163
- Administration, Oral
- Animals
- Benzamides
- Cell Line
- Cell Proliferation -- drug effects
- Drug Resistance, Neoplasm -- drug effects
- Female
- Focal Adhesion Protein-Tyrosine Kinases -- antagonists & inhibitors
- Gastrointestinal Stromal Tumors -- drug therapy
- Imatinib Mesylate
- Mice
- Mice, Nude
- Morpholines -- administration & dosage
- Mutation -- genetics
- Piperazines -- therapeutic use
- Proto-Oncogene Proteins c-akt -- metabolism
- Proto-Oncogene Proteins c-kit -- genetics
- Pyrimidines -- therapeutic use
- Substrate Specificity
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Publication Type: Journal Article
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