Intraspinal cord delivery of IGF-I mediated by adeno-associated virus 2 is neuroprotective in a rat model of familial ALS. [electronic resource]
Producer: 20090310Description: 473-81 p. digitalISSN:- 1095-953X
- Amyotrophic Lateral Sclerosis -- physiopathology
- Animals
- Cell Survival
- Dependovirus -- genetics
- Disease Models, Animal
- Disease Progression
- Female
- Genetic Therapy
- Genetic Vectors
- Injections, Spinal
- Insulin-Like Growth Factor I -- genetics
- Male
- Motor Activity
- Motor Neurons -- physiology
- Rats
- Rats, Sprague-Dawley
- Rats, Transgenic
- Sex Factors
- Spinal Cord -- metabolism
- Survival Analysis
- Transduction, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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