SARS-CoV proteins decrease levels and activity of human ENaC via activation of distinct PKC isoforms. [electronic resource]
Producer: 20090414Description: L372-83 p. digitalISSN:- 1040-0605
- Acute Lung Injury -- etiology
- Amiloride -- pharmacology
- Animals
- Cell Line
- Endocytosis
- Enzyme Activation
- Epithelial Sodium Channels -- genetics
- Exocytosis
- Female
- Gene Expression
- Humans
- In Vitro Techniques
- Isoenzymes -- antagonists & inhibitors
- Membrane Glycoproteins -- genetics
- Oocytes -- metabolism
- Patch-Clamp Techniques
- Protein Kinase C -- antagonists & inhibitors
- Protein Kinase Inhibitors -- pharmacology
- Pulmonary Edema -- etiology
- Recombinant Proteins -- genetics
- Severe acute respiratory syndrome-related coronavirus -- genetics
- Spike Glycoprotein, Coronavirus
- Transfection
- Viral Envelope Proteins -- genetics
- Viral Proteins -- genetics
- Viroporin Proteins
- Xenopus
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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