Apoptosis induced by 2-acetyl-3-(6-methoxybenzothiazo)-2-yl-amino-acrylonitrile in human leukemia cells involves ROS-mitochondrial mediated death signaling and activation of p38 MAPK. [electronic resource]
Producer: 20090410Description: 55-63 p. digitalISSN:- 1872-7980
- Acrylonitrile -- analogs & derivatives
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Benzothiazoles -- pharmacology
- Caspases -- physiology
- Dose-Response Relationship, Drug
- HL-60 Cells
- Humans
- Mitochondria -- physiology
- Reactive Oxygen Species -- metabolism
- U937 Cells
- p38 Mitogen-Activated Protein Kinases -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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