Haploinsufficiency of activation-induced deaminase for antibody diversification and chromosome translocations both in vitro and in vivo. [electronic resource]
Producer: 20090223Description: e3927 p. digitalISSN:- 1932-6203
- Animals
- Antibody Diversity -- genetics
- B-Lymphocytes -- enzymology
- Chromosomes, Mammalian -- genetics
- Cytidine Deaminase -- genetics
- Haploidy
- Hyperplasia
- Immunoglobulin Class Switching -- genetics
- Immunoglobulin Heavy Chains -- genetics
- Interleukin-6 -- immunology
- Lymph Nodes -- immunology
- Lymphocyte Activation -- immunology
- Mice
- Mice, Transgenic
- Proto-Oncogene Proteins c-myc -- genetics
- Recombination, Genetic -- genetics
- Somatic Hypermutation, Immunoglobulin -- genetics
- Translocation, Genetic
- AICDA (Activation-Induced Cytidine Deaminase)
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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