2-(3,4-Dichlorophenyl)-N-methyl-N-[2-(1-pyrrolidinyl)-1-substituted- ethyl]-acetamides: the use of conformational analysis in the development of a novel series of potent opioid kappa agonists. [electronic resource]
Producer: 19910312Description: 181-9 p. digitalISSN:- 0022-2623
- Acetamides -- chemical synthesis
- Analgesia
- Analgesics -- chemical synthesis
- Animals
- Female
- Guinea Pigs
- In Vitro Techniques
- Indicators and Reagents
- Male
- Mice
- Mice, Inbred Strains
- Molecular Conformation
- Molecular Structure
- Muscle, Smooth -- drug effects
- Naloxone -- metabolism
- Pyrrolidines -- chemical synthesis
- Receptors, Opioid -- drug effects
- Receptors, Opioid, mu
- Structure-Activity Relationship
- Vas Deferens -- drug effects
- X-Ray Diffraction
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Publication Type: Comparative Study; Journal Article
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