Inhibition of glycogen synthase kinase-3beta downregulates total tau proteins in cultured neurons and its reversal by the blockade of protein phosphatase-2A. [electronic resource]
Producer: 20090227Description: 66-75 p. digitalISSN:- 1872-6240
- Analysis of Variance
- Animals
- Blotting, Western
- Calcineurin -- metabolism
- Calcineurin Inhibitors
- Cells, Cultured
- Cyclin-Dependent Kinase 5 -- antagonists & inhibitors
- Enzyme Inhibitors -- pharmacology
- Glycogen Synthase Kinase 3 -- antagonists & inhibitors
- Glycogen Synthase Kinase 3 beta
- Indoles -- pharmacology
- Lithium Chloride -- pharmacology
- Neurons -- drug effects
- Okadaic Acid -- pharmacology
- Oximes -- pharmacology
- Phosphorylation -- drug effects
- Protein Phosphatase 2 -- antagonists & inhibitors
- Purines -- pharmacology
- Rats
- Rats, Wistar
- Roscovitine
- Tacrolimus -- pharmacology
- tau Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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