Amentoflavone stimulates apoptosis in B16F-10 melanoma cells by regulating bcl-2, p53 as well as caspase-3 genes and regulates the nitric oxide as well as proinflammatory cytokine production in B16F-10 melanoma cells, tumor associated macrophages and peritoneal macrophages. [electronic resource]
Producer: 20090115Description: 207-18 p. digitalISSN:- 1359-4117
- Animals
- Apoptosis -- drug effects
- Biflavonoids -- pharmacology
- Caspase 3 -- genetics
- Cells, Cultured
- Cytokines -- metabolism
- Gene Expression Regulation, Neoplastic -- drug effects
- Granulocyte-Macrophage Colony-Stimulating Factor -- metabolism
- Interleukin-1beta -- metabolism
- Interleukin-6 -- metabolism
- Macrophages -- drug effects
- Melanoma, Experimental -- genetics
- Mice
- Mice, Inbred C57BL
- Nitrates -- metabolism
- Nitric Oxide -- metabolism
- Nitric Oxide Synthase Type II -- genetics
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- RNA, Messenger -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Tumor Necrosis Factor-alpha -- metabolism
- Tumor Suppressor Protein p53 -- genetics
No physical items for this record
Publication Type: Journal Article
There are no comments on this title.
Log in to your account to post a comment.